CJC Peptide (CJC-1295): Growth Hormone Releasing Secretagogue
CJC peptide (specifically CJC-1295) is a synthetic 29-amino acid peptide analog of naturally occurring Growth Hormone-Releasing Hormone (GHRH). By binding to GHRH receptors on anterior pituitary somatotrophs, CJC-1295 stimulates the endogenous release and synthesis of growth hormone (GH) and Insulin-Like Growth Factor 1 (IGF-1).
CJC-1295 is synthesized in two distinct formulations:
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CJC-1295 No DAC (Modified GRF 1-29): Features a short half-life (~30 minutes), creating natural, physiological GH pulses.
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CJC-1295 with DAC (Drug Affinity Complex): Binds to blood albumin to extend its half-life to 6–8 days, providing continuous baseline GH elevation.
When stacked with ghrelin receptor agonists like Ipamorelin, CJC-1295 produces a synergistic pulse that amplifies growth hormone release beyond what either peptide achieves alone.
Key CJC-1295 & Ipamorelin Blend Benefits
Combining CJC peptide with Ipamorelin activates two independent pituitary pathways simultaneously:
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Natural Growth Hormone Pulses: Enhances natural, secretagogue-driven GH output without shutting down baseline endocrine function.
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Body Composition & Lipolysis: Accelerates subcutaneous and visceral fat loss while promoting lean muscle tissue preservation.
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Enhanced Deep Sleep Architecture: Increases slow-wave delta sleep cycles, accelerating physiological cellular repair.
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Accelerated Tissue & Joint Recovery: Stimulates collagen synthesis, repairing tendon, ligament, and skeletal muscle tissue.
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Clean Safety Profile: CJC-1295 No DAC and Ipamorelin do not cause significant spikes in prolactin or cortisol.
CJC-1295 Ipamorelin Dosage Chart
Proper cjc-1295 no dac ipamorelin dosage per day depends on research objectives and administration frequency:
| Research Goal | CJC-1295 (No DAC) Dose | Ipamorelin Dose | Daily Frequency | Administration Timing |
| Tolerance / Starter | 100mcg | 100mcg | 1x daily | Bedtime (fasted 2-3 hrs) |
| General Wellness & Sleep | 100mcg | 100mcg – 200mcg | 1x daily | 30 minutes before bed |
| Fat Loss & Recomp | 100mcg – 200mcg | 200mcg – 300mcg | 2x daily | Fasted morning + before bed |
| Muscle Recovery & Athletic | 100mcg – 200mcg | 200mcg – 300mcg | 2–3x daily | Fasted AM, Post-workout, Bedtime |
Protocol Note: The saturation dose for CJC-1295 No DAC is ~100mcg per injection. Doses above this threshold yield diminishing returns on GHRH receptors, which is why stacking with Ipamorelin is the industry standard.
Administration Rules & Reconstitution
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Empty Stomach Requirement: Injections must occur when blood glucose and insulin levels are low (at least 2–3 hours after eating). Elevated insulin or somatostatin blunts growth hormone release.
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Syringe Drawing: CJC-1295 No DAC and Ipamorelin are chemically compatible and can be drawn into the same U-100 insulin syringe prior to injection.
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Cycle Length: Standard research cycles run for 8 to 16 weeks, followed by a 4 to 8 week off-cycle break to maintain pituitary sensitivity.
Product Specifications & Storage
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Compound: CJC-1295 No DAC (Modified GRF 1-29) / CJC-1295 + Ipamorelin Blend
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Form: Lyophilized freeze-dried powder vial (2mg / 5mg / 10mg)
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Purity: Premium Laboratory Grade (>98% HPLC Certified)
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Storage Instructions: Store unopened vials frozen (-20°C). After reconstitution with Bacteriostatic Water, store refrigerated between 2°C and 8°C and use within 28 days.
Frequently Asked Questions (FAQs)
What is the main difference between CJC-1295 with DAC and CJC-1295 No DAC?
CJC-1295 with DAC has a half-life of 6 to 8 days, providing constant, elevated growth hormone levels. CJC-1295 No DAC (Mod GRF 1-29) has a ~30-minute half-life, allowing for controlled, physiological growth hormone pulses.
Why are CJC-1295 and Ipamorelin frequently combined?
CJC-1295 stimulates the GHRH receptor while Ipamorelin stimulates the ghrelin/GHS-R1a receptor. Stimulating both pathways concurrently results in a synergistic growth hormone release greater than using either peptide alone.
What is the ideal daily timing for a CJC-1295 No DAC Ipamorelin dose?
Injections are best administered 30 minutes before bed or first thing in the morning. A strict 2-to-3-hour fast prior to injection is required to prevent blood glucose/insulin from blocking GH release.
How long does a standard CJC peptide cycle last?
Typical research protocols run on an 8- to 16-week cycle followed by 4 to 8 weeks of rest to preserve pituitary receptor responsiveness.
Where can I buy high-purity CJC peptide online?
You can order batch-tested, high-purity CJC-1295 (with or without DAC) and CJC/Ipamorelin blends directly online from Peptide Works with verified HPLC certificates of analysis.
Disclaimer: This product is strictly sold as a research chemical for laboratory development and educational purposes only. Not for human or animal consumption.




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