LL-37 Peptide (Cathelicidin): Immune Defense & Tissue Repair
ll 37 peptide is a 37-amino-acid antimicrobial peptide (AMP) belonging to the human cathelicidin family. Cleaved from the CAP-18 precursor protein, LL-37 plays a critical role in host immune defense by disrupting pathogen cell membranes and modulating inflammatory responses.
When researchers look to source LL-37 peptide, purity and batch verification are essential. LL-37 is widely evaluated in immunology, gut health, biofilm degradation, and tissue regeneration due to its broad-spectrum action against bacteria, viruses, and fungi.
Key LL-37 Peptide Benefits in Research
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Broad-Spectrum Antimicrobial Action: Direct-killing action against Gram-positive and Gram-negative bacteria, viruses, and fungal strains by neutralizing membrane structures.
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Biofilm Disruption: Disrupts established bacterial biofilms, making it a primary focus in persistent infection research.
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Gut Barrier & Mucosal Repair: Promotes intestinal mucosal healing and tightness, making LL-37 gut health studies prominent in auto-immune and leaky gut models.
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Angiogenesis & Wound Healing: Accelerates tissue repair, re-epithelialization, and new blood vessel formation in wound management models.
LL-37 Peptide Dosage & Protocols
Because LL-37 exerts potent signaling effects, research protocols require controlled administration and dose escalation:
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Subcutaneous Research Protocols: Common research dosages range from 100mcg to 250mcg daily or every other day over a short cycle (14 to 30 days).
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Targeted Topicals / Irrigation: Applied in laboratory tissue culture or topical models at micro-molar concentrations for wound-healing evaluation.
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LL-37 Side Effects: Generally well-tolerated in research models. Higher dosages can trigger transient localized redness, mild burning at the injection site, or minor inflammatory spikes due to rapid pathogen clearance (Herxheimer-like response).
Product Specifications & Handling
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Compound: LL-37 (Human Cathelicidin Fragment)
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Form: Freeze-dried (lyophilized) powder vial
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Purity: Premium Research Standard (>98% HPLC Verified)
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Storage Instructions: Store unopened vials frozen at -20°C. Reconstitute with sterile Bacteriostatic Water, keep refrigerated (2°C to 8°C), and use within 28 days.
Frequently Asked Questions (FAQs)
What is LL-37 peptide used for?
LL-37 is an antimicrobial peptide researched for its ability to clear bacterial pathogens, break down biofilms, support gut mucosal integrity, and accelerate tissue repair.
How does cathelicidin LL-37 support gut health?
In gut health models, LL-37 helps regulate balanced gut microbiota, strengthens the mucosal barrier, and suppresses hyper-inflammatory immune triggers in the intestinal tract.
What is the standard LL-37 peptide dosage in research?
In scientific literature, typical research protocols evaluate 100mcg to 250mcg administered subcutaneously 1 to 2 times daily over a brief multi-week cycle.
Where is the best place to buy LL-37 peptide online?
You can order certified, high-purity LL-37 peptide vials directly online from Peptide Works with guaranteed HPLC testing certificates and fast delivery.
Disclaimer: This product is strictly sold as a research chemical for laboratory development and educational purposes only. Not for human or animal consumption.




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